{"id":3,"date":"2020-07-16T15:01:35","date_gmt":"2020-07-16T15:01:35","guid":{"rendered":"https:\/\/box2328\/cgi\/addon_GT.cgi?s=GT::WP::Install::EIG+%28lcaselab%29+-+10.0.87.61+%5BWordPress%3b+\/var\/hp\/common\/lib\/WordPress.pm%3b+295%3b+Hosting::gap_call%5D\/?page_id=3"},"modified":"2026-08-26T01:46:24","modified_gmt":"2026-08-26T01:46:24","slug":"home","status":"publish","type":"page","link":"https:\/\/lcaselab.org\/","title":{"rendered":"Welcome"},"content":{"rendered":"\n<hr class=\"wp-block-separator has-text-color has-background is-style-wide\" style=\"background-color:#ffffff;color:#ffffff\"\/>\n\n\n\n<div class=\"alignnormal\"><div id=\"metaslider-id-44\" style=\"width: 100%;\" class=\"ml-slider-3-113-1 metaslider metaslider-nivo metaslider-44 ml-slider ms-theme-default\" role=\"region\" aria-label=\"New Slideshow\" data-height=\"400\" data-width=\"1000\">\n    <div id=\"metaslider_container_44\">\n        <div class='slider-wrapper theme-default'><div class='ribbon'><\/div><div id='metaslider_44' class='nivoSlider'><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2020\/07\/ReconstituteActin-371x148.jpg\" height=\"400\" width=\"1000\" title=\"Actin-Polymerization\" alt=\"\" class=\"slider-44 slide-46 msDefaultImage\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2020\/07\/CellImage-pFAK-Actin15-1-512x204.jpg\" height=\"400\" width=\"1000\" title=\"Focal Adhesions\" alt=\"\" class=\"slider-44 slide-48 msDefaultImage\" \/><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2020\/07\/FAK_Well3_30min_6-e1594938688264-240x96.jpg\" height=\"400\" width=\"1000\" title=\"phase separation\" alt=\"\" class=\"slider-44 slide-49 msDefaultImage\" \/><\/div><\/div>\n        \n    <\/div>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-background is-style-wide\" style=\"background-color:#ffffff;color:#ffffff\"\/>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\">How do cells sense and respond to information in their environment?<\/h4>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:24px\">The Case Lab studies the physical principles that underly cell adhesion and cell signaling in mammalian cells. For example, receptor clustering and higher-order assembly with cytoplasmic proteins can create compartments with unique biochemical and biophysical properties. We use quantitative experimental approaches from biochemistry, molecular biophysics, and cell biology to study cell adhesion and cell signaling pathways and how they are misregulated in diseases like cancer.&nbsp;<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"727\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-scaled.png\" alt=\"\" class=\"wp-image-869\" style=\"width:552px;height:132px\" srcset=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-scaled.png 2560w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-300x85.png 300w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-1024x291.png 1024w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-768x218.png 768w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-1536x436.png 1536w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/mit_lockup_std-three-line_rgb_mit-red-2048x582.png 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2409\" height=\"243\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB.png\" alt=\"\" class=\"wp-image-868\" srcset=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB.png 2409w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB-300x30.png 300w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB-1024x103.png 1024w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB-768x77.png 768w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB-1536x155.png 1536w, https:\/\/lcaselab.org\/wp-content\/uploads\/2026\/08\/KI_logo_new_horizontal_RGB-2048x207.png 2048w\" sizes=\"auto, (max-width: 2409px) 100vw, 2409px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<h3 class=\"wp-block-heading has-text-align-center\">Our research is supported by:<\/h3>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"399\" height=\"126\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/10\/NIHNewInnovatorGraphic.jpg\" alt=\"\" class=\"wp-image-481\" style=\"width:621px;height:196px\" srcset=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/10\/NIHNewInnovatorGraphic.jpg 399w, https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/10\/NIHNewInnovatorGraphic-300x95.jpg 300w\" sizes=\"auto, (max-width: 399px) 100vw, 399px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/05\/AFOSR_2-300x300.jpeg\" alt=\"\" class=\"wp-image-434\" style=\"width:307px;height:307px\" srcset=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/05\/AFOSR_2-300x300.jpeg 300w, https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/05\/AFOSR_2-150x150.jpeg 150w, https:\/\/lcaselab.org\/wp-content\/uploads\/2022\/05\/AFOSR_2.jpeg 400w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"224\" height=\"225\" src=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2025\/07\/NSF.jpeg\" alt=\"\" class=\"wp-image-764\" srcset=\"https:\/\/lcaselab.org\/wp-content\/uploads\/2025\/07\/NSF.jpeg 224w, https:\/\/lcaselab.org\/wp-content\/uploads\/2025\/07\/NSF-150x150.jpeg 150w\" sizes=\"auto, (max-width: 224px) 100vw, 224px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>How do cells sense and respond to information in their environment? The Case Lab studies the physical principles that underly cell adhesion and cell signaling in mammalian cells. For example,&hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-3","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lcaselab.org\/index.php?rest_route=\/wp\/v2\/pages\/3","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lcaselab.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lcaselab.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lcaselab.org\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/lcaselab.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3"}],"version-history":[{"count":4,"href":"https:\/\/lcaselab.org\/index.php?rest_route=\/wp\/v2\/pages\/3\/revisions"}],"predecessor-version":[{"id":872,"href":"https:\/\/lcaselab.org\/index.php?rest_route=\/wp\/v2\/pages\/3\/revisions\/872"}],"wp:attachment":[{"href":"https:\/\/lcaselab.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}